Strong R&D commitment to developing therapeutics against SARS-CoV-2 virus Overall R&D investment up 7% to 3.7 billion EUR in 2020 (18.9% of net sales) Positive business performance despite the impact of COVID-19 pandemicTotal human pharmaceuticals and animal health net sales in 2020 across the Middle East, Turkey, and Africa witnessed 11% growth,Boehringer Ingelheim Lebanon allocated $1.14 Million of aid support following the devastating Beirut harbour explosion in August 2020Boehringer Ingelheim Lebanon\u2019s donated medical supplies to the Lebanese Pulmonary Society as part of its commitment to support in the fight against the ongoing COVID-19 pandemicOutlook 2021: only moderately optimistic in view of COVID-19 Beirut, Lebanon March 25, 2021 \u2013 Boehringer Ingelheim stepped up its investments in R&D significantly in 2020 in pursuit of innovative medicines and therapies for diseases for which no satisfactory treatments are available. In particular, efforts to research potential COVID-19 related therapies were accelerated. The company spent 3.7 billion EUR on R&D, 7% more than in the previous year. This represents the highest annual investment in R&D in the 136-year history of the research-driven biopharmaceutical company. \u201cWe started our R&D for potential COVID-19 therapies early in the first quarter of 2020, recognizing the urgent need to help,\u201d said Hubertus von Baumbach, Chairman of the Board of Managing Directors. \u201cTogether with many partners worldwide, this work is ongoing for the benefit of patients infected with the virus.\u201d \u201cDespite the numerous obstacles we have faced due to the ongoing pandemic as well as the tragic explosion at the Beirut harbor in August 2020, Boehringer Ingelheim is proud of its commitment and efforts made over the past year to ensure the supply of needed medications as well as the provision of support to patients and wider Lebanese community,\u201d said Fouad Jeweidi, Levant and Iraq Country Head at Boehringer Ingelheim. \u201cThis is a testament to the company\u2019s tireless efforts and commitment towards the provision of innovative healthcare products for the ultimate advancement of human and animal health across the country and wider region. We will continue to work together with local partners to strive towards the improvement of the country\u2019s health care offering and economy, to ensure that patients across Lebanon are provided access to the most effective medical options and solutions available.\u201d Additionally, in light of the explosion that impacted the harbor of Beirut on August 4th, 2020, Boehringer Ingelheim stood in solidarity with the Lebanese community through the allocation of $1.14 Million of aid to support local relief operations. This included the replenishment of medication stocks lost at the warehouse due to the devastating explosion as well as the support of local non-governmental organizations through the renovation of damaged hospitals and centers. Boehringer Ingelheim employees in Lebanon also stepped up to support the local community by volunteering and providing relief through meal donations and clean-up efforts. Meanwhile, building on its vast knowledge in various therapeutic areas, such as respiratory diseases and virology, Boehringer Ingelheim is engaged in several projects aimed at finding medical solutions to treat COVID-19. In December 2020, the company announced together with Cologne University Hospital (UKK), the University of Marburg (UMR), and the German Center for Infection Research (DZIF) the initiation of Phase I\/IIa clinical investigation of BI 767551, a SARS-CoV-2 neutralizing antibody and potential new therapeutic and prophylactic option to reduce the potential risk and effects of a COVID-19 infection. Other COVID-19 initiatives include the research and development of SARS-CoV-2 antibodies that can neutralize the virus, small molecules to inhibit its replication, and therapy development to prevent micro coagulation (blood clots). Solid performance despite COVID-19 pandemic 2020 was yet another good year for Boehringer Ingelheim, although the effects of the COVID-19 pandemic were omnipresent. All of its businesses contributed positively to net sales and operating income. The company globally recorded net sales of 19.57 billion EUR, a 3% increase compared to the previous year. Foreign currency headwinds had a considerable impact; adjusted for currency effects, net sales rose by 5.6% year on year. The Middle East, Turkey and Africa region also witnessed considerable business growth despite the impact of the ongoing pandemic that the region has been faced with since 2020. The company recorded total net sales of 515 million EUR, an 11% increase compared to the 2019 year, with net sales of 463 million EUR and 52 million EUR recorded for Human Pharma and Animal Health respectively. During 2020, Boehringer Ingelheim META\u2019s immense efforts secured it recognition as the second fastest growing pharmaceutical company across the top 25 pharmaceutical corporations in the region, further ranking 14 among the top 25 multinational pharmaceutical companies in 2020, Boehringer Ingelheim META human pharma business recorded a total growth rate of 20%. Emphasis on profitable growth and protecting liquidity \u201cWe are quite pleased with the results we achieved in 2020, considering the challenging conditions we faced,\u201d said Christoph Raab, Head of Finance and Administration at Boehringer Ingelheim Middle East, Turkey and Africa. \u201cWe met our ambitious targets, both in terms of our contribution to the wellbeing of humans, pets and livestock, and our business performance. This allows us to continue to invest even more in R&D, as well as in the long-term opportunities we have identified, most notably in the fields of digital and data technologies, oncology and infectious diseases.\u201d Continued high investments in fixed assets The company made investments in its market presence and legal entities across the META region, including moving to new offices in various markets to accommodate for the increase in business operations as well as the number of employees in across the region. Boehringer Ingelheim now has legal offices in the United Arab Emirates, South Africa, Turkey, Lebanon, Kuwait and Qatar, with legal entities in Saudi Arabia, Turkey and South Africa, and scientific offices present in Algeria and Egypt, with a plan to extend in Morocco and Kenya. Furthermore, Boehringer Ingelheim Lebanon launched numerous initiatives in support of patients throughout the country. This includes patient education programs on disease areas including diabetes, idiopathic pulmonary fibrosis, and cardiovascular diseases, to help people living with these diseases in Lebanon better manage their conditions and improve their quality of life. Human Pharma \u2013 Strong growth across all regions At 14.42 billion EUR, net sales of human pharmaceuticals grew strongly by 5.8% (year on year and adjusted for currency effects) and accounted for 74% of total net sales. All regions contributed to the strong results in Human Pharma including META. At 383 million EUR, net sales of human pharmaceuticals across the Middle East, Turkey and Africa increased by 20.1% in 2020. Medicines for the treatment of cardiovascular and metabolic diseases, as well as respiratory diseases, remain the most important contributors to net sales globally. For instance, Boehringer Ingelheim\u2019s diabetes medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes, remains the biggest revenue contributor in Human Pharma, generating net sales of 2.48 billion EUR (2019: 2.15 billion EUR). This medication reduces the risk of cardiovascular death in adults with type 2 diabetes who have known cardiovascular disease. The company\u2019s pulmonary fibroses diseases medication was the company\u2019s second-strongest revenue contributor for the first time, with net sales of 2.06 billion EUR and growth of 41% (year on year and adjusted for currency effects) (2019: 1.49 billion EUR). This medicine is used for the treatment of patients with idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease (SSc-ILD) and, in some countries, other chronic fibrosing interstitial lung diseases with a progressive phenotype. High R&D investment in Human Pharma R&D investments in the Human Pharma business amounted to 3.28 billion EUR or 22.8% of net sales. There are around 100 projects across all phases of the research process. The goal is for 75% of these projects to be either the first molecule in their active ingredient class or in a new therapeutic area. Over 50% of them have breakthrough potential. The focus of R&D in Human Pharma lies on cardiovascular and metabolic diseases, oncology, respiratory, immunology, diseases of the central nervous system and retinal health. Animal Health \u2013 Strong performance in a highly competitive market The Animal Health business of Boehringer Ingelheim is one of the largest providers of veterinary vaccines and medicines and has a strong presence in the livestock and pets\u2019 segments. In 2020, the Animal Health business delivered a strong performance in a highly competitive market and grew by 5% (year on year and adjusted for currency effects) by posting net sales of 4.12 billion EUR. The pet antiparasitic segments developed successfully and outperformed expectations. EUR). The parasiticide NEXGARD\u00ae remained the company\u2019s best-selling product, with growth of 12% (year on year and adjusted for currency effects) and net sales of 804 million EUR. Within its META markets, Boehringer Ingelheim\u2019s Animal Health business has improved health in the livestock, equine, and poultry industries, through operating in 69 countries, with 62 distributors and agents and 28 commercially active countries across the region. The META region currently stands at number seven in the company\u2019s overall Animal Health business worldwide and is the second-fasted growing animal health company in META. Furthermore, as part of Boehringer Ingelheim Lebanon\u2019s commitment to support in the fight against the ongoing COVID-19 pandemic, the company donated medical supplies to the Lebanese Pulmonary Society. The donation included surgical face masks, sanitizers, gloves, oximeters, infra-thermometers, face shields and N-95 masks. The initiative came as part of the company\u2019s Global Support Program launched in April 2020 to bring financial relief to communities in need worldwide. During 2020, Boehringer Ingelheim also launched numerous initiatives in the region in line with the company\u2019s values and commitment towards fostering an inclusive, supportive, and healthy work environment. This included the launch of its Parental Leave across META, to support its commitment towards diversity and inclusion, as well as reinforce the company\u2019s values of supporting employees to maintain a healthy balance between work and family life. In Lebanon particularly, numerous sessions were also conducted to help provide employees with emotional support, as well as assess what other measures could be implemented during the current crisis faced by the country. In acknowledgment of the impact of the ongoing COVID-19 pandemic on the work and private lives of employees, Boehringer Ingelheim also provided a period of collective time off globally, including META, for all employees by the end of 2020 to relax, recover and re-energize. Outlook 2021: Boehringer Ingelheim expects a slight year on year increase in net sales on a comparable basis The ongoing COVID-19 pandemic and a more challenging industry environment with increasing price pressure in several key markets is expected to have an impact on Boehringer Ingelheim\u2019s results in 2021. Assuming that the approved vaccines and other medicines currently undergoing approvals help curb the COVID-19 pandemic, the company expects strong general market growth for prescription pharmaceuticals. For 2021, Boehringer Ingelheim expects to achieve a slight year on year increase in net sales on a comparable basis. The 2020 Annual Report can be found here: https:\/\/annualreport.boehringer-ingelheim.com\/ Boehringer Ingelheim Boehringer Ingelheim is working on breakthrough therapies that improve the lives of humans and animals. As a leading research-driven biopharmaceutical company, the company creates value through innovation in areas of high unmet medical need. Founded in 1885 and family-owned ever since, Boehringer Ingelheim takes a long-term perspective. Approximately 52,000 employees serve more than 140 markets in the three business areas, Human Pharma, Animal Health, and Biopharmaceutical Contract Manufacturing. Learn more at www.boehringer-ingelheim.com.